Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.

Updated: 2017 Aug. 1

| Home | Kinexus | Contact | Credits

Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PPP1R8 All Species: 35.45
Human Site: T125 Identified Species: 65
UniProt: Q12972 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q12972 NP_002704.1 351 38479 T125 G A S T R A Y T L R E K P Q T
Chimpanzee Pan troglodytes XP_001150604 378 41336 T125 G A S T R A Y T L R E K P Q T
Rhesus Macaque Macaca mulatta XP_001112289 378 41328 T125 G A S T R A Y T L R E K P Q T
Dog Lupus familis XP_865789 355 39236 T129 G A S T R A Y T L R E K P Q T
Cat Felis silvestris
Mouse Mus musculus Q8R3G1 351 38509 T125 G A S T R A Y T L R E K P Q T
Rat Rattus norvegicus NP_001101381 351 38521 T125 G A S T R A Y T L R E K P Q T
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001518825 234 26189 P23 C P S W A G K P P P G L H L D
Chicken Gallus gallus NP_001026062 354 38600 T126 G A S T R A Y T L R E K P Q T
Frog Xenopus laevis NP_001083528 346 37932 T123 G A S T R M Y T L R E K P Q A
Zebra Danio Brachydanio rerio NP_001094422 351 38384 T123 G A S T R V Y T L R E K P Q T
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_611177 383 42555 I116 G A S T R N Y I L R E R P S G
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans NP_492781 302 33933 F91 M D S S H G T F L G N V R L R
Sea Urchin Strong. purpuratus XP_001199058 347 38163 I119 G A S S R S Y I L R E K P Q T
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 91.8 91.2 89 N.A. 98 97.7 N.A. 65.8 88.6 82.9 77.7 N.A. 47.5 N.A. 39 51.5
Protein Similarity: 100 91.8 91.5 90.4 N.A. 98.5 98.5 N.A. 66 93.2 89.7 88 N.A. 62.1 N.A. 53.8 67.5
P-Site Identity: 100 100 100 100 N.A. 100 100 N.A. 6.6 100 86.6 93.3 N.A. 66.6 N.A. 13.3 80
P-Site Similarity: 100 100 100 100 N.A. 100 100 N.A. 6.6 100 86.6 93.3 N.A. 73.3 N.A. 20 93.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 85 0 0 8 54 0 0 0 0 0 0 0 0 8 % A
% Cys: 8 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 8 0 0 0 0 0 0 0 0 0 0 0 0 8 % D
% Glu: 0 0 0 0 0 0 0 0 0 0 85 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 8 0 0 0 0 0 0 0 % F
% Gly: 85 0 0 0 0 16 0 0 0 8 8 0 0 0 8 % G
% His: 0 0 0 0 8 0 0 0 0 0 0 0 8 0 0 % H
% Ile: 0 0 0 0 0 0 0 16 0 0 0 0 0 0 0 % I
% Lys: 0 0 0 0 0 0 8 0 0 0 0 77 0 0 0 % K
% Leu: 0 0 0 0 0 0 0 0 93 0 0 8 0 16 0 % L
% Met: 8 0 0 0 0 8 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 8 0 0 0 0 8 0 0 0 0 % N
% Pro: 0 8 0 0 0 0 0 8 8 8 0 0 85 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 0 0 77 0 % Q
% Arg: 0 0 0 0 85 0 0 0 0 85 0 8 8 0 8 % R
% Ser: 0 0 100 16 0 8 0 0 0 0 0 0 0 8 0 % S
% Thr: 0 0 0 77 0 0 8 70 0 0 0 0 0 0 70 % T
% Val: 0 0 0 0 0 8 0 0 0 0 0 8 0 0 0 % V
% Trp: 0 0 0 8 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 85 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _